The project initiated with designing and constructing a certain radiation generator, specifically for this therapeutic method. Then via body phantom experiments, the accurate measurement confirmed the remarkable advantage of new method as follow:

NTM * absorbed dose

Treatment Benefit   =

CRT**absorbed dose

Results and discussion: The experiments results by phantom proved that “NTM” is 50 times (5000 percent) more effective to compare with conventional radiation   therapy.

In-vitro experiments on various cancer cells cultures and also in-vivo experiences on laboratory animals showed that in live cultures environment, the efficiency rate of this method is higher with in 80 up to 150 times-as an average of 119times (119oo percent)-to compare with usual radiation therapy for all kinds of cancers. In this manner, relatively low energies transmit into the sound tissue of the exposed areas; however, multifold of fatal dose is absorbed by neoplastic cells. Thus, the whole radiation therapy plan could be ended in one section.

Cancers are one of the severe adversities for human being. Because of their complicated treatment and lack of their complete prevention; nevertheless, relevant researches have been allocated to overcome these illness in the whole world. (4) Enforcement of this project could be an intention to a new approach to cancer therapy via treatment rate elevation up to more than one hundred times.

In conventional radiotherapy which is today’s usual cancer treatment procedure, with consideration of statistical measurement and cancer suffered patients mortalities rate, the lack of complete treatment ability of this illness   has been signed.  There are the other procedures such as chemotherapy and surgery for predominating cancer treatment intricacies; however, those methods’ problems, procedure restriction and details are out of our discussion in this topic. One of the important aspects of the new method preference is its unique coordination to two above-mentioned methods for absolute malignancy therapy. There are two

general procedures for today’s radiotherapy as follow: Internal and external treatments that internal treatment includes intra tissue, intra-cavity, intra-venous, and intra-arterial are just practical for a limited cases; consequently, tumor cells do not receive fatal dose and regeneration of neoplastic cells would occur, besides cancer cells invasion into the other tissues.

This condition would be increased the degree of metastasis; thus, the probability of the cancer therapy could fall off to zero (9).

This new procedure is to approach the effective cancer therapy with optimal prognosis and malignant relapse prevention. Meanwhile, sound tissues remain undamaged because of relatively low radiation intensity; consequently, mortality rate of cancer could be decreased.

Fig (1): The first prototype of NTM device.

Fig (2): (A):  Survival curves of NTM, (B): Common Radiation Therapy

Fig(3): The  above picture  has shown In-vivo survival curve of mice counted alive lymphocytes

1- Exam group;

2– injected mice by RRG agents, 3.5% dead lymphocytes;

3– common radiotherapy procedures, 5.5% dead lymphocytes;

4– NTM procedures, 95% dead lymphocytes.

Equivalent to research of “NTM” assessment on neo plastic cells in terms of in-vivo and in-vitro, a linked research was applied on relevant drugs through the new system.

Associated drugs are combined in two main parts: one acts as a carrier that has tendency to absorb in to the certain malignant tumor, another transfers via carrier to the neo-plastic cells, meanwhile specific “NTM” drugs act similar to all type of malignancies. Evidently, nuclear medicine kits were also used as a carrier for this complex. At present, for several groups of tumors, NTM are available, consequently that allowed the clinical practice of drugs on some volunteer patients.

However, Ethic Commission of Medical Science University authorized us that at the first stage of clinical practice, we should enforce the new procedure only on the patient who would suffer hepato cell carcinoma. There by, we submit, in brief explanation, relevant C.T. Scanning image evidence of some patients.

With no exception, all the patients who were referred to treat by new method were despaired from the other methods, because of the end stage condition. For relative less incident of this disease (hepato cell carcinoma), in addition to treating physician’s written verification compulsion to confirm volunteer patients hopelessness from the other current procedures, hence number of the specimens was less.

Without exception all patients’ malignancy was undergone to complete necrosis, nevertheless the patients are not to be confined to bed

through this new procedure, hence it would be thoughtful of our therapeutic system privilege.

Specialist simply applies relevant tumor “Radio-Radio Generator Drugs”-by monitor control -on the day clinic-referring patient. After being assured to transfer the optimal amount of drug in to the certain tumor, he expose the tumor by local beam within one to three minute then releases the patient, whilst patient is schedule for only one session treatment.

In later stage, the patient is to set up under periodical care at home, besides CT Scanning investigation at the certain time. The submitted volunteer patients CT Scanning evidence, clearly shows the definite effectiveness of the new method. However, these patients were in the worst clinical condition, after one session of “NTM” procedure, their sickness relatively diminished, hence their appetite turn acceptable, their weight increased in addition to their motility, and physical movement ability improvement.

The malignancy necrosis is explicit for volunteer patients by imaging confirmation, meanwhile, all patients’ identification with their associated CT Scanning, before and after procedure are enclosed.

2-A: The super selective angiographic CT scanning central slice of 60 years old man suffering from Hepato Cellular carcinoma has shown a measured mass about 850 Cm³ in his liver (before “NTM” ).

2-B: The same patient’s CT scanning central slice, six month from a session of “NTM” has shown sixty per cent of tumor dissolving that confirms such a   decisive therapeutic method that is effective even for one session.

3-A: Patient’s CT scanning, at age of 62 has shown progressive malignancy with the mass about 500 Cm³ (before “NTM”).

3-B: The same patient’s CT scanning, six month duration from therapy by “NTM” has sh necrosis and dissolving of tumor (10 month after previous CT scanning).

4-A: Patient’s CT scanning, at age of 77 has shown progressive malignancy with the mass about 540 Cm³ (before “NTM”).

4-B: The same patient’s CT scanning, 3 month duration from therapy by “NTM” has shown necrosis and dissolving of tumor.

4-C: The same patient’s CT scanning , six month duration from therapy by “NTM” has shown necrosis and dissolving of tumor.